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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '5a381cbeee2fd6df94f18b99a1cdedb21cbf418b774691ecaf1aa9eddc1e9f27' 
  AND token = '9C2qG8zSRmdgKwpYrjhUdqD6pwarWMnt1IQxkRG9dDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00007

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}