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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '16a78f2479d2b8b4fd8772812b7a4378984c1b220f6a2940d3d2654cd0cb2385' 
  AND token = 'YcRoPo7pb4XMnJa6Uvrak6yjY5Fgs73HxZNMkhoMjwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}