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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '121c1b3d10e16c3966a27a45e9370664294cd2aa08cee05f33a4761ac3e7c2e4' 
  AND token = 'SNX0pAxnssNWg4R08TRKj1UsWlt0QjXPzFbz2xl5Hrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}