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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '187ccb485ddf6a84522d75369f32a2bc6eca05b64358566b3763c51fbb97e332' 
  AND token = '2MhEXsG9Tx3erYTF1NbrT9Cn5WvdAUSOcUQvNfJsn9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}