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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = 'c121cf4fcdd00e6fe1907bb32113289a5db34763a9c86a843c47a17371db3220' 
  AND token = 'j6CbXdMjSShKgpRlHps3O0BjK01oZYzBszp1Yb0KoQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}