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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '50c3810748a1734922201a46ed47860515f62699282ad39dbd880d78eafbed33' 
  AND token = 'mwcnmEHd3xbHbnFFDJXAUzdaA3CuMWSILqH9t3NbRVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}