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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = 'a1243fe0e10820ba2b3aabe2a1bf778d01ba38e9d058ad14d84709908c35ca82' 
  AND token = 'vZkAxNjwgEfUsNo7KCudZN6P1VIgvQpJA2h+tYeyQRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}