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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '2e1f01323bb484d5cfac531eee3fba6adf0dccb9ee209cc17451b3f14dbb3869' 
  AND token = 'yXSv9UlLf1R4ZFBbhPTvLeiNhKSLpg+GI0HOYdAeUiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}