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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = 'afc6be9f55f720aa78bb57c6f1f5c4c6480aea586c6b6624c3094b788603afb4' 
  AND token = '+E7RVgakS6BZCb60xjnYZe+611pSUPwNc+6EDYtWeWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}