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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '21150447068abee17c5802f06d5e79748744df7cc1db56fc7e5e2d35b2498728' 
  AND token = 'kAtdVRQOBsG6niPEPtnU00qPXX3bWav8npGn9ElMmyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}