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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '5bd4e813a3689bc0310d41c102c2e242d1b41b29a5141e9f389524d2839cd0de' 
  AND token = 'ru+zXJp4e42RxVF8eOkaJVLoZrIFrDu5jRrUhqx6uWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}