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SELECT 
  1 
FROM 
  vi_lock_keys 
WHERE 
  key_id = '4e348bffd7a2a01d009cedcaa3e5881b7c405d0b8ef8a8b60407e5580167e386' 
  AND token = '6F6TOAjbrGy1xDvFrSsaGwDhlFx42wXeR+WGhgTFY5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}